In Vivo and In Vitro Multiple Protocols SMPCs and SCs

Single cell transcriptomes of hPSC-derived skeletal muscle progenitor cells (SMPCs; MP subpopulations from the myogenic subsets) obtained using three different protocols (HX protocol, Xi et al., Cell Rep, 2017; JC protocol, Chal et al., Nat Biotechnol, 2015; MS protocol, Shelton et al., Stem Cell Rep, 2014) are aligned to human prenatal SMPCs and postnatal juvenile […]

In Vivo and In Vitro HX Protocol SMPCs and SCs

Single cell transcriptomes of hPSC-derived skeletal muscle progenitor cells (SMPCs; MP subpopulations from the myogenic subsets) obtained using the HX protocol (Xi et al., Cell Rep, 2017) at different time points of differentiation are aligned to human prenatal SMPCs and postnatal juvenile and adult skeletal muscle stem cells (satellite cells; SCs). SMPCs generated from hPSCs […]

In Vivo SMPCs and SCs

Single cell transcriptomes of prenatal skeletal muscle progenitor cells (SMPCs; MP subpopulations from the myogenic subsets) from different stages of embryonic and fetal development as well as postnatal juvenile and adult skeletal muscle stem cells (satellite cells; SCs) are combined into a single dataset. The developmental trajectory of SMPCs and SCs are analyzed using diffusion […]